NMR Spectroscopy Facility
This facility hosts five high resolution NMR spectrometers located in three laboratories in the SOP buildings. The capability of instrumentation allows to conduct research in variety of research areas including natural products research and small molecules.
Welcome to the NMR Core Facility at the University of Mississippi
The NMR Core Facility is location at the School of Pharmacy and provides access to both local and external users.
Our facility hosts five high resolution NMR spectrometers located in three laboratories in the SOP buildings. The capability of instrumentation allows us to conduct research in a variety of research area including natural products research and small molecules.
All spectrometers have capability to perform NMR experiments on 1H, 19F, 13C, 13P, and 15N nuclei.
The Goals of the NMR Core Facility
The aim of the NMR facility is to provide UM students, research staff, faculty, as well as external users wish access to equipment and training on a variety of NMR methods. Currently, the facility is equipped with four spectrometers available for general use.
These instruments support a variety of interdisciplinary projects ranging from chemistry to structural biology.
NMR Services
Our NMR facility provides the following services for faculty, researchers, students, and external users:
- Training of new and existing users via webinars, individual remote and hands-on sessions on a variety of NMR methods and data processing
- Access to the facility and equipment of trained users
- Collection of NMR data upon request
- Consulting services
What instruments are available?
The NMR Core Facility has four instruments for use.
- North: 400 MHz Avance IIIHD spectrometer equipped with 5mm RT Broad Band Probe (BBFO) North wish VT capability. Location: TCRC West B15
- South: 400 MHz Avance IIIHD spectrometer equipped with mm RT Broad Band Prove (BBFO) with VT capability. Location: TCRC West B15
- 500 MHz Avance IIIHD spectrometer equipped with 5mm Prodiogy H/F-BBO cryprobe, BCU-I temperature controller. Location: TCRC West B15
- 600 MHz Avance III spectrometer equipped with 5mm RT Broad Band Prove (BBFO) and VT capabilities. Location: TCRC East B3013
Interested in using one of our instruments? Make a reservation with NMR today!
What are the rates to use NMR Core Facility instruments?
The NMR Core Facility provides access to some of the most advanced NMR services available in the region. Hourly rates for the Core services are provided in the table below.
| Service | UM Internal Rate | External Rate, Federal | External Rate, Non-Federal |
| Bruker 400 MHz North/South | $5.00 | $5.00 | $7.00 |
| Bruker 500 MHz with Prodigy Probe | $15.00 | $15.00 | $22.00 |
Bruker 600 MHz | $11.00 | $11.00 | $16.00 |
| Consultation/NMR manager time | $38.00 | $38.00 | $55.00 |
Invoicing and Payment
All requests for services must be submitted through our online scheduling system. When completing the project application online, please include all payment information.
Invoices will be sent out during the second week of the month for services provided in the previous month. If payment information changes, please call or email us to update.
Reserving NMR Services
A reservation is required for the NMR services. The Infinity scheduling system developed by Idea ELAN is used for all NMR reservations. Please register or log in to request services and to create and manage NMR reservations.
Authentication using your Ole Miss web ID and password is required.
Users can only reserve for their own use and not for someone else. Users who scheduled NMR services will be billed for the services used.
Cancellations
Reservation can be canceled 15 min prior the reservation.
If the user missed the reservation for more than 15 minutes, remainder of time slot will be available to other users for the reservations.
Additional Training
Training is performed by the NMR facility manager. Users must follow the instructions of the staff.
- A refresher course is required if you did not use the facility for more than 12 month.
Certain types of experiments, which are not included in the basic training require additional training session which should be scheduled separately.
Education and Outreach
NMR facility supports education of students at various levels. Advanced NMR can be incorporated into the graduate and undergraduate coursed. Theory and hands-on and practical session for students s are available.
A graduate course on advanced NMR is offered at School of Pharmacy at the University of Mississippi.
NMR facility also supports STEM education and encourages participation of the students from community colleges and K-12 schools. Core is open for collaboration with students, teachers, and faculty in order to assist with development of research projects and providing access to the instrument.
This approach aims to gain interest of the young students in STEM field and providing access to the modern instrumentation.
Please contact NMR facility staff for educational opportunities.
Scheduling a Tour
Core staff host variety of tours to the NMR facility to provide demonstration of capabilities of the instrumentation or for educational purposes for interested users including K-12 students, teachers, external researchers, college students, and faculty. Please contact us for additional information or for scheduling a tour.
NMR Core Facility Policies
To access the NMR Core Facility, students, research scientists, and external users must respect the following policies:
- NMR facility is available for all students, research scientists, and external users. All users are treated equally.
- Only trained people are allowed to use the facility. Additional training is required for 600 MHz spectrometer. All new users must contact the NMR facility manager directly to schedule the initial training session.
- Do not change the settings of the instrumentation unless you are authorized to do so.
- In case the problem immediately contact the NMR manager describing the details of the problem.
- Report all violations to the NMR facility manager.
- Multiple violations will lead to "refusal of access" to the facility.
- Repair and opportunity cost (downtime of the system used for maintenance) will be billed directly to the user/Principal investigator who cause the problem.
- Users are responsible for their data. All spectra must be saved in appropriate folder on the computer and transferred promptly to their computer using remote connection or portable media.
- Do not leave your samples once your experiments have been finished. Unlabeled, broken samples, as well as those which were left unattended for more than 5 days will be discarded.
- Users must follow the instructions of the staff.
- All users must follow standard lab safety protocols. No food or drink is allowed in the facility at any time.
Acknowledgments
Co-authorship is appreciated and may be requested in the following instances: significant intellectual contribution to experimental design, analysis and/or interpretation of data, and preparation of data for the purpose of publication.
It is also expected that users will let the NMR facility staff know if the data obtained with the NMR is used in grant applications.