My research focuses on the isolation, characterization, and biological evaluation of secondary metabolites from natural sources, with particular interest in cytotoxicity, anti-inflammatory, and immunomodulatory activities.
Research Interests
- Pharmaceutical Sciences
- Drug Discovery
- Natural Product Chemistry
- Extraction and Purification Methods
- NMR, HPLC, LC-MS, GC-MS -Analytical and Spectroscopic Methods
Biography
Dr. Aydogan is a Postdoctoral Research Associate at the University of Mississippi with a Pharm.D. degree and a background in pharmaceutical sciences, particularly in natural products. Her research focuses on the extraction, isolation, and structural elucidation of bioactive secondary metabolites, as well as their pharmacological evaluation and potential therapeutic applications.
With over five years of experience in natural product chemistry, pharmacognosy, and phytochemistry, she has collaborated on interdisciplinary research projects that bridge chemistry and biology in pharmaceutical sciences. Her work includes identifying biologically active compounds from botanical sources, optimizing extraction and purification techniques, and assessing the bioactivity of natural products, including cytotoxicity, immunomodulatory, and anti-inflammatory properties. She is proficient in advanced analytical techniques such as NMR, HRMS, HPLC, UPLC, UV/Vis, CD, X-ray, and QM/NMR for characterizing natural compounds.
Dr. Aydogan values continuous learning and has participated in specialized training programs such as the Nature Masterclass, NIH OITE-Raising a Resilient Scientist Program, Torrey Pines Leadership Development Programs at Sanford Burnham Prebys, ACS Postdoc to Faculty Workshop, the CITI Program, and the NIH Career Symposium. These experiences have strengthened her research methodologies, scientific communication, and collaborative skills. Her contributions through research, publications, and presentations aim to support the advancement of natural product-based drug discovery and foster a deeper understanding of phytotherapeutics and dietary supplements.
Astracondensatol D: A 6/6/5/6 Cycloartane Triterpenoid from Astragalus condensatus: Fadime Aydoğan, Pankaj Pandey, Frank R. Fronczek, Ikhlas A. Khan, Zulfiqar Ali, and Amar. G. Chittiboyina. Organic Letters, 2025
Revisiting the Cyclocephagenols via Astragalus condensatus: Structural Insights and Configurational Revision: Aydoğan. F., Pandey, P., Fronczek, F.R., Ali, Z., Ferreira, D. Khan, I. A.,Chittiboyina, A.G. Journal of Natural Products, 2024, 87(11), pp. 2657–2664.
Is Baikiain in Tara Flour a Causative Agent for the Adverse Events Associated with the Recalled Frozen French Lentil & Leek Crumbles Food Product? - A Working Hypothesis. Chittiboyina, Amar G.Ali, ZulfiqarAvula, Bharathi, Khan, Shabana I., Mir, Tahir M., Zhang, Jin, Aydoğan, Fadime, Zulfiqar, Fazila, Techen, Natascha, Parveen, Iffat, Pandey, Pankaj, Adams, Sebastian J. Wang, Yan-Hong,Zhao, Jianping, Marshall, Gailen D., Pugh, Nirmal D. Khan, Ikhlas A. Chemical Research in Toxicology, 2023, 36(6), pp. 818–821
Neo-Clerodanes from Teucrium divaricatum subsp. divaricatum and their biological activity assessment. Aydoğan, F., Zulfiqar A., Karaalp, C., Khan, I.A. Bedir, E. Phytochemistry Letters, 2023, 54, pp. 45–49
An unprecedented diterpene with three new neoclerodanes from Teucrium sandrasicum O. Schwarz. Aydoğan, F., Anouar, E.H., Aygün, M., ... Karaalp, C., Bedir, E. Journal of Molecular Structure, 2021, 1231, 129919.
Education
B.A. Pharmacy, EGE University (2012)